Loss of E-Cadherin Expression Correlates With Ki-67 in Head and Neck Squamous Cell Carcinoma

Autor:	DUMITRU, CRISTINA STEFANIA, CEAUSU, AMALIA RALUCA, COMSA, SERBAN, RAICA, MARIUS
Rok vydání:	2022
Předmět:	Pharmacology Cancer Research Ki-67 Antigen Antigens CD Head and Neck Neoplasms Squamous Cell Carcinoma of Head and Neck Carcinoma Squamous Cell Humans Cadherins General Biochemistry Genetics and Molecular Biology Research Article
Zdroj:	In Vivo
ISSN:	1791-7549 0258-851X
DOI:	10.21873/invivo.12814
Popis:	Background/Aim: The aim of the study was to evaluate the correlation between the rate of proliferation and immunohistochemical expression of E-cadherin, and their predictive role in patients with head and neck squamous cell carcinoma (HNSCC). Materials and Methods: Samples were collected from 50 patients with HNSCC, and the expression of Ki-67 and E-cadherin was evaluated by immunohisto-chemistry (IHC). Previously, samples were conventionally stained with haematoxylin and eosin for histological diagnosis and grade. Results: High E-cadherin expression was predominantly associated with less differentiated tumours (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fccc3447280eb9f7bb7e7c91d8f055 https://doi.org/10.21873/invivo.12814 Zobrazit plný text záznamu