Direct Oral Anticoagulants: An Overview for the Interventional Radiologist
| Autor: | Caroline Shiach, Gaurav Sundar, Pradesh Kumar, Rajeev Ravi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Administration Oral Single step Hemorrhage 030204 cardiovascular system & hematology Radiology Interventional 030226 pharmacology & pharmacy 03 medical and health sciences 0302 clinical medicine Thrombin Coagulation cascade Thromboembolism Radiologists Medicine Humans Radiology Nuclear Medicine and imaging Dosing Intensive care medicine medicine.diagnostic_test business.industry Warfarin Anticoagulants Interventional radiology Surgery Clinical Practice Oral vitamin Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Cardiovascular and interventional radiology. 40(3) |
| ISSN: | 1432-086X |
| Popis: | The direct oral anticoagulants (DOACs) have emerged as a good alternative for the treatment of thromboembolic diseases, and their use in clinical practice is increasing rapidly. The DOACs act by blocking the activity of one single step in the coagulation cascade. These drugs act downstream in the common pathway of the coagulation cascade by directly antagonising the action of thrombin or factor Xa. The development of DOACs represents a paradigm shift from the oral vitamin K antagonists such as warfarin. This article aims to describe the properties of the currently available DOACs including pharmacology and dosing. We also address the strategies for periprocedural management and reversal of anticoagulation of patients treated with these agents. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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