Human iPSC banking: barriers and opportunities
| Autor: | Patrick C.H. Hsieh, Ching-Ying Huang, Yu-Che Cheng, Yueh-Ting Chiu, Chien-Yu Ting, Chun-Lin Liu, Martin W. Nicholson |
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| Rok vydání: | 2019 |
| Předmět: |
Endocrinology
Diabetes and Metabolism Induced Pluripotent Stem Cells Clinical Biochemistry Cell- and Tissue-Based Therapy lcsh:Medicine Review Regenerative Medicine Regenerative medicine 03 medical and health sciences 0302 clinical medicine Humans Pharmacology (medical) Induced pluripotent stem cell Molecular Biology Biomedicine Biological Specimen Banks 030304 developmental biology Cell bank 0303 health sciences Drug discovery business.industry lcsh:R Biochemistry (medical) Cell Biology General Medicine Personalized medicine 3. Good health Induced pluripotent stem cell (iPSC) Engineering ethics Business 030217 neurology & neurosurgery Stem Cell Transplantation |
| Zdroj: | Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-14 (2019) Journal of Biomedical Science |
| ISSN: | 1423-0127 |
| Popis: | The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based drug discovery and toxicity assessment. Over the past 10 years, several initiatives have been established that aim to collect and generate a large amount of human iPSCs for scientific research purposes. In this review, we compare the construction and operation strategy of some iPSC banks as well as their ongoing development. We also introduce the technical challenges and offer future perspectives pertaining to the establishment and management of iPSC banks. |
| Databáze: | OpenAIRE |
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