Translocation (6;16) in a case of granulosa cell tumor of the ovary

Autor:	Bogusław Nedoszytko, A. Verhest, J.-C. Noel, Janusz Limon, J.M. Dangou, Philippe Simon
Rok vydání:	1992
Předmět:	Adult congenital hereditary and neonatal diseases and abnormalities Cancer Research Monosomy medicine.medical_specialty Granulosa cell Aneuploidy Chromosomal translocation Ovary Biology Translocation Genetic Dicentric chromosome hemic and lymphatic diseases Genetics medicine Humans Molecular Biology Granulosa Cell Tumor Ovarian Neoplasms Cytogenetics Karyotype medicine.disease Molecular biology medicine.anatomical_structure Karyotyping Chromosomes Human Pair 6 Female Chromosomes Human Pair 16 circulatory and respiratory physiology
Zdroj:	Cancer genetics and cytogenetics. 60(1)
ISSN:	0165-4608
Popis:	We performed a cytogenetic study of an ovarian granulosa cell tumor (GCT). Tumor cells showed a translocation (6;16); the full karyotype was 45,XX−6,dic(6;16)(q11;q22)/44,XX,−6, −22,dic(6;16)(q11;q22),−22/46,XX,−6,dic(6;16)(q11;q22),+dic(6;16)(q11;q22). This is the second case of GCT with structural changes of chromosome 6 leading to loss of 6q material.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ee6604b9b78ab7211d3dc690618514 https://pubmed.ncbi.nlm.nih.gov/1591705 Zobrazit plný text záznamu