Uncharted surgical therapy for acquired perforating dermatoses

Autor: Mohammad Bashar Izzat, Ali Kahila, Ahmad Walid Izzat, Ali Zamlout, Sami Alashi
Rok vydání: 2022
Předmět:
Zdroj: Asian Cardiovascular and Thoracic Annals. 31:148-150
ISSN: 1816-5370
0218-4923
DOI: 10.1177/02184923221136761
Popis: Acquired perforating dermatoses represent an uncommon group of chronic papulonodular dermatoses of unknown aetiology, characterized clinically by intense itching; and histopathologically by transepidermal elimination of dermal components. Definitive targeted pharmacological approaches are lacking, and the disease is usually refractory to therapy. We report here a case of rapid remission of acquired perforating dermatosis following simple thymectomy. If a role for the thymus in the pathogenesis of acquired perforating dermatoses was to be established, this could pave the way for a yet uncharted surgical therapy for these debilitating conditions.
Databáze: OpenAIRE