Cyclic estrous-like behavior in a spayed cat associated with excessive sex-hormone production by an adrenocortical carcinoma
| Autor: | José A. Ramos-Vara, S. Kathleen Salisbury, Sara L. Bennett, J. Catharine Scott-Moncrieff, Erika Meler, A.T. Peter, James F. Naughton |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
endocrine system
medicine.medical_specialty medicine.medical_treatment Estrous Cycle Adrenocorticotropic hormone Cat Diseases Human chorionic gonadotropin Internal medicine Adrenocortical Carcinoma medicine Animals Adrenocortical carcinoma Gonadal Steroid Hormones Small Animals Progesterone Estrous cycle Estradiol business.industry Adrenal gland 17-alpha-Hydroxyprogesterone Adrenalectomy Androstenedione medicine.disease Adrenal Cortex Neoplasms Treatment Outcome Endocrinology medicine.anatomical_structure Cats Female business hormones hormone substitutes and hormone antagonists Endocrine gland Hormone |
| Zdroj: | Journal of Feline Medicine and Surgery. 13:473-478 |
| ISSN: | 1532-2750 1098-612X |
| DOI: | 10.1016/j.jfms.2011.02.002 |
| Popis: | A 15-year-old, spayed female domestic shorthair cat was evaluated for 1-year duration of cyclic intermittent estrous behavior. Diagnostic testing performed before referral, including baseline progesterone concentration, human chorionic gonadotropin (hCG) hormone stimulation test and surgical exploratory laparotomy, had remained inconclusive for a remnant ovary. Evaluation of sex hormones before and after adrenocorticotropic hormone (ACTH) administration revealed increased basal concentrations of androstenedione, estradiol, progesterone, and 17α−hydroxyprogesterone and normal ACTH-stimulated hormone concentrations. Enlargement of the right adrenal gland was identified by abdominal ultrasound. The cat underwent an adrenalectomy and histopathology of the excised adrenal gland was consistent with an adrenocortical carcinoma. Clinical signs resolved immediately following surgery, and most hormone concentrations declined to within or below the reference interval (RI) by 2 months after surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|