Antidepressants during pregnancy

Autor: Marlies E. Brouwer, Johannes J. Duvekot, Claudi L H Bockting, Esther M. Knijff, G. S. de Wolf, Mijke P. Lambregtse-van den Berg, Witte J.G. Hoogendijk, Nina M Molenaar, Huibert Burger
Přispěvatelé: Adult Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Mental Health, APH - Personalized Medicine, APH - Quality of Care, Master Evidence Based Practice, APH - Digital Health, Psychiatry, Obstetrics & Gynecology, Life Course Epidemiology (LCE), Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Reproductive Origins of Adult Health and Disease (ROAHD)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Midwifery, 61, 29-35. Churchill Livingstone
Midwifery, 61, 29-35. ELSEVIER SCI LTD
ISSN: 0266-6138
Popis: Background and objectives: prescription rates of antidepressants during pregnancy range from 2–3% in The Netherlands to 6.2% in the USA. Inconclusive evidence about harms and benefits of antidepressants during pregnancy leads to variation in advice given by gynaecologists and midwives. The objective was to investigate familiarity with, and adherence to the Dutch multidisciplinary guideline on Selective Serotonin Reuptake Inhibitor (SSRI) use during pregnancy by gynaecologists and midwives in the Netherlands. Methods: an online survey was developed and send to Dutch gynaecologists and midwives. The survey consisted mainly of multiple-choice questions addressing guideline familiarity and current practice of the respondent. Also, caregiver characteristics associated with guideline adherence were investigated. Findings: a total of 178 gynaecologists and 139 midwives responded. Overall familiarity with the Dutch guideline was 92.7%. However, current practice and advice given to patients by caregivers differed substantially, both between gynaecologists and midwives as well as within both professions. Overall guideline adherence was 13.9%. Multivariable logistic regression showed that solely caregiver profession was associated with guideline adherence, with gynaecologists having a higher adherence rate (OR 2.10, 95%CI 1.02–4.33) than midwives. Key conclusion: although reported familiarity with the guideline is high, adherence to the guideline is low, possibly resulting in advice to patients that is inconsistent with guidelines and unwanted variation in current practice. Implications for practice: further implementation of the recommendations as given in the guideline should be stimulated. Additional research is needed to examine how gynaecologists and midwives can be facilitated to follow the recommendations of the clinical guideline on SSRI use during pregnancy.
Databáze: OpenAIRE
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