Exploring the Rare Etiology of Severe Anemia in an Immunocompromised Patient
| Autor: | Neel S Patel, Rajesh Thirumaran, Sana Mulla, Vihitha Thota, Ruqqiya Mustaqeem, Jakub Trawinski, Ashish Bains, Keerthy Joseph |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Anemia
Pure red cell aplasia Infectious Disease b19 parvovirus infection urologic and male genital diseases Severe anemia Blood loss hemic and lymphatic diseases Pathology Medicine Erythroid Precursor Cells business.industry General Engineering Immunocompromised patient Hematology medicine.disease impaired erythropoiesis bone marrow biopsy medicine.anatomical_structure pure red cell aplasia immunohistochemical stain Immunology Etiology Bone marrow business intravenous immunoglobulin (ivig) |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Pure red cell aplasia (PRCA) is a rare cause of profound anemia, marked by very low reticulocyte count and near to complete absence of erythroid precursor cells in the bone marrow. PRCA can be congenital such as in the case of children with Diamond- Blackfan anemia or acquired, which is often triggered by exposure to certain viruses or drugs. Management depends on the underlying etiology of PRCA. Here, we present the case of a young male with underlying acquired immunodeficiency syndrome, who presented with a hemoglobin of 2.6 g/dL, initially thought to be secondary to gastrointestinal blood loss, but was later discovered to have parvovirus-induced PRCA. |
| Databáze: | OpenAIRE |
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