Factors associated with hospital readmissions among patients with COVID‐19: A single‐center experience
Autor: | Jean-Gabriel Coignet, Zurab Azmaiparashvili, Glenn Eiger, Ruchika Bhargav, Geneva Guarin, Robert DeJoy, Kevin Bryan Lo, Gabriel Patarroyo-Aponte, Ammaar Wattoo, Janani Rangaswami, Grace Salacup |
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Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Time Factors Coronavirus disease 2019 (COVID-19) Population novel coronavirus Comorbidity Logistic regression Single Center Patient Readmission Coronary artery disease 03 medical and health sciences 0302 clinical medicine Risk Factors COVID‐19 Virology Diabetes mellitus Internal medicine medicine Humans 030212 general & internal medicine education Research Articles Aged Retrospective Studies education.field_of_study SARS-CoV-2 readmission business.industry Mortality rate Significant difference COVID-19 Middle Aged Pennsylvania medicine.disease mortality Logistic Models Infectious Diseases Multivariate Analysis Female 030211 gastroenterology & hepatology business Research Article |
Zdroj: | Journal of Medical Virology |
ISSN: | 1096-9071 0146-6615 |
DOI: | 10.1002/jmv.27104 |
Popis: | Objectives Identify factors associated with readmission after an index hospital admission for Coronavirus Disease 2019 (COVID-19) infection in a single center serving an underserved and predominantly minority population. Methods This retrospective descriptive study included 275 patients who tested COVID-19 positive via reverse transcriptase-polymerase chain reaction assay at our institution and who survived the index hospitalization. Outcomes Main outcomes were 1-month and 6-month readmission rates after an index hospitalization for COVID-19. Mortality rate among the readmitted patients was also determined. Factors independently associated with readmission were investigated using multivariable logistic regression. Results A final sample of 275 patients were included. The mean age was 64.69 ±14.64 (SD) 133 (48%) were female and 194 (70%) were African American. Their chronic medical conditions included hypertension 203 (74%) and diabetes mellitus 121 (44%). After the hospitalization, 1-month readmission rate was 7.6%, while 6-month readmission rate was 24%. 9% of patients who were readmitted subsequently died. Coronary artery disease (CAD) was significantly associated with 6-month readmission OR 2.15 (95% CI 1.04-4.44; p=0.039) after adjustment for age, gender, ethnicity and comorbidities. Readmissions were due to cardiac, respiratory, and musculoskeletal symptoms. Hispanic ethnicity was associated with increased readmission OR 3.16 (95% CI 1.01-9.88; p=0.048). No significant difference was found between inflammatory markers or clinical outcomes during the index hospitalization among patients who were readmitted compared to those who were not. Conclusions A significant number of patients hospitalized for COVID-19 may be readmitted. Presence of CAD is independently associated with high rates of 6-month readmission. This article is protected by copyright. All rights reserved. |
Databáze: | OpenAIRE |
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