The Impact of Social Factors on Human Immunodeficiency Virus and Hepatitis C Virus Co-Infection in a Minority Region of Si-Chuan, the People's Republic of China: A Population-Based Survey and Testing Study
Autor: | Caiting Dong, Wenhong Lai, Li Liu, Song Zhibin, Daying Wei, Lei Nan, Yihui Yang, Z. Jennifer Huang, Huang Jun, Honglu Liu, Ying Hu, Qixing Wang, Frank Y. Wong, Zhang Jianxun, Maria C. Martin, Deng Hongxia, Bin Deng, Wen Yang, Guangming Qin, Linglin Zhang |
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Rok vydání: | 2014 |
Předmět: |
Male
Viral Diseases Epidemiology Gastroenterology and hepatology Hepacivirus lcsh:Medicine HIV Infections medicine.disease_cause Hepatitis Drug Users Immunodeficiency Viruses Drug control Risk Factors Young adult lcsh:Science Multidisciplinary biology Coinfection virus diseases Hepatitis C Middle Aged Substance abuse Infectious hepatitis Sexual Partners Infectious Diseases Medical Microbiology Viral Pathogens Female Research Article Adult China Adolescent Hepatitis C virus Sexually Transmitted Diseases Microbiology Infectious Disease Epidemiology Young Adult Sex Factors medicine Humans Microbial Pathogens Liver diseases Medicine and health sciences business.industry lcsh:R HIV Biology and Life Sciences Odds ratio medicine.disease biology.organism_classification Social Epidemiology Socioeconomic Factors Immunology lcsh:Q business Demography |
Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 7, p e101241 (2014) |
ISSN: | 1932-6203 |
Popis: | BACKGROUND: While many human immunodeficiency virus (HIV) studies have been performed in Liangshan, most were focused only on HIV infection and based on a sampling survey. In order to fully understand HIV and hepatitis C virus (HCV) prevalence and related risk factors in this region, this study implemented in 2009, included a survey, physical examination, HIV and HCV test in two towns. METHODS: All residents in two towns of the Butuo county were provided a physical examination and blood tests for HIV and HCV, and then followed by an interview for questionnaire. RESULTS: In total, 10,104 residents (92.4%) were enrolled and 9,179 blood samples were collected for HIV and HCV testing, 6,072 were from individuals >14 years old. The rates of HIV, HCV, and HIV/HCV co-infection were 11.4%, 14.0%, and 7.7%, respectively for >14-year-old residents. The 25-34 yr age group had the highest prevalence of HIV, HCV, and HIV/HCV co-infections, reaching 24.4%, 26.2% and 16.0%, respectively. Overall, males had a much higher prevalence of all infections than females (HIV: 16.3% vs. 6.8%, HCV: 24.6% vs. 3.9%, HIV/HCV co-infected: 14.7% vs. 1.1%, respectively; P = 0.000). Approximately half of intravenous drug users tested positive for HIV (48.7%) and 68.4% tested positive for HCV. Logistic regression analysis showed that five factors were significantly associated with HIV and HCV infection: gender (odds ratio [OR] = 5.8), education (OR = 2.29); occupation (student as reference; farmer: OR = 5.02, migrant worker: OR = 6.12); drug abuse (OR = 18.0); and multiple sexual partners (OR = 2.92). Knowledge of HIV was not associated with infection. CONCLUSION: HIV and HCV prevalence in the Liangshan region is very serious and drug use, multiple sexual partners, and low education levels were the three main risk factors. The government should focus on improving education and personal health awareness while enhancing drug control programs. |
Databáze: | OpenAIRE |
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