Pelvic exenterations for gynecologic cancers: A retrospective analysis of a 30-year experience in a cancer center
Autor: | M Provansal, A. Tallet, D Mokart, Eric Lambaudie, G. Houvenaeghel, L Sabiani, Sophie Knight |
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Rok vydání: | 2018 |
Předmět: |
Adult
medicine.medical_specialty Multivariate analysis Genital Neoplasms Female medicine.medical_treatment 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Retrospective analysis Humans Aged Retrospective Studies 030219 obstetrics & reproductive medicine Pelvic exenteration business.industry Patient Selection Cancer Retrospective cohort study Common Terminology Criteria for Adverse Events General Medicine Middle Aged Plastic Surgery Procedures medicine.disease Primary tumor Pelvic Exenteration Surgery Survival Rate Radiation therapy Treatment Outcome Oncology 030220 oncology & carcinogenesis Female Neoplasm Recurrence Local business |
Zdroj: | European Journal of Surgical Oncology. 44:1929-1934 |
ISSN: | 0748-7983 |
Popis: | INTRODUCTION The objective of this study was to report a 30-year experience of PE for gynecologic malignancies in a cancer center. MATERIALS AND METHODS A retrospective study was conducted at Institut Paoli-Calmette including patients who underwent PE for gynecologic malignancies. Four periods were evaluated: P1 before 1992, P2 between 1993 and 1999, P3 between 2000 and 2006 and P4 after 2006. The study evaluated the number of PE performed during each period, the type of PE, its level, indication, location of the primary tumor, patient age, previous radiotherapy ≥45 Gy, the rate of "curative" PE and exenteration-related reconstructive techniques. 90-day post-operative mortality and morbidity using the National Cancer Institute's Common Terminology Criteria for Adverse Events (NCI-CTCAE) v 4.03 were reported. RESULTS 277 PE were performed. The number of PE performed for recurrences rose during the study period (p = 0.042), PE performed for central tumors increased during P3 (64.4%) and P4 (67.4%) (p |
Databáze: | OpenAIRE |
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