Cytogenetic study of patients with carcinoma of the colon and rectum: Particular C-band variants as possible markers for cancer proneness
| Autor: | Isaac Halbrecht, D. Kimchi, E. Antebi, Fiorella Shabtai, D. Klar, Jacob Hart |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Genetic Markers Male Oncology Cancer Research medicine.medical_specialty Colorectal cancer Rectum Adenocarcinoma Biology Malignancy Internal medicine Genetics Carcinoma medicine Humans Molecular Biology Aged Chromosome Aberrations Chromosomes Human 6-12 and X Polymorphism Genetic Rectal Neoplasms Incidence (epidemiology) Chromosomes Human 1-3 Cancer Karyotype Middle Aged medicine.disease Chromosome Banding medicine.anatomical_structure Karyotyping Colonic Neoplasms Immunology Female Disease Susceptibility |
| Zdroj: | Cancer Genetics and Cytogenetics. 14:235-245 |
| ISSN: | 0165-4608 |
| DOI: | 10.1016/0165-4608(85)90189-x |
| Popis: | A possible involvement of chromosomal heterochromatic polymorphisms in propensity to cancer has been considered and discussed by several investigators who studied groups of patients presenting with different forms of malignancy. We report a cytogenetic study on the circulating lymphocytes of patients suffering from colorectal carcinoma, most of whom were of European origin. Significantly increased incidence of polymorphisms of chromosomes #1 and #9 was found, especially partial inversions (PI). Emphasis is given to the problem of selecting adequate controls, which must be as homogeneous as possible. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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