Radiological–pathological correlation of yolk sac tumor in 20 patients
| Autor: | AiQun Cai, RuoWei Chen, Gui-Xiao Xu, Yang-Kang Li, JianBang Lin, MingYao Wu, Yu Zheng |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Iohexol Contrast Media 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Humans Medicine Radiology Nuclear Medicine and imaging Yolk sac Child Retrospective Studies Radiological and Ultrasound Technology business.industry Endodermal Sinus Tumor Infant General Medicine Radiological pathological correlation Rare tumor medicine.anatomical_structure Child Preschool 030220 oncology & carcinogenesis Radiological weapon Female Radiology Tomography X-Ray Computed business |
| Zdroj: | Acta Radiologica. 57:98-106 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1177/0284185114561916 |
| Popis: | Background Yolk sac tumor (YST) is a rare tumor. Familiarity of its radiological characteristics may permit preoperative diagnosis and improve surgical management of patients. However, a detailed description of the imaging features of YST with pathological correlation in particular is scarce. Purpose To investigate computed tomography (CT) findings of YSTs with pathological correlation. Material and Methods CT images of 20 patients with pathologically proven YST were retrospectively reviewed. The location, size, margin, internal architecture, and pattern and degree enhancement of the lesion were evaluated. Radiological findings were correlated with pathological results. Results The locations of 20 tumors were distributed between the testis ( n = 3), ovary ( n = 6), sacrococcygeal area ( n = 6), rectum ( n = 1), and mediastinum ( n = 4). The median age was 13 years. On CT images, all tumors were seen as oval ( n = 14) or irregular ( n = 6), well-defined ( n = 16) or ill-defined ( n = 4) masses with a mean size of 9.7 cm. The lesions were solid cystic ( n = 10), entirely solid ( n = 6), or predominantly cystic ( n = 4). Intratumoral hemorrhage, calcification, and fatty tissue were seen in nine, three, and two tumors, respectively. Discontinuity of the tumor wall was seen in eight tumors. After contrast media administration, most tumors showed heterogeneous moderate to marked enhancement ( n = 7) or heterogeneous marked enhancement ( n = 9). Enlarged intratumoral vessels were seen in 17 tumors. Conclusion YST usually appears as a large solid-cystic mass with intratumoral hemorrhage, capsular tear, marked heterogeneous enhancement, and enlarged intratumoral vessels on CT images. Intratumoral calcification and fatty tissue, although rare, may indicate a mixed YST containing teratoma component. |
| Databáze: | OpenAIRE |
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