Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements
| Autor: | Kenneth D. Tew, Laurent Gaté, H Tapiero, D. Machover |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Vitamin
medicine.medical_specialty Homocysteine Nutritional Status Folic Acid Deficiency medicine.disease_cause chemistry.chemical_compound Folic Acid Neoplasms Internal medicine medicine Animals Humans Uracil Pharmacology Catabolism Dietary intake DNA General Medicine Diet Bioavailability Oxidative Stress Tetrahydrofolate Dehydrogenase Endocrinology Folic acid chemistry Lipid Peroxidation Oxidative stress Intracellular |
| Zdroj: | Biomedicine & Pharmacotherapy. 55:381-390 |
| ISSN: | 0753-3322 |
| DOI: | 10.1016/s0753-3322(01)00077-4 |
| Popis: | Folate (folic acid, folacin) is an essential vitamin that is found in nature. Folates contain the core chemical structure of pteroylglutamic acid, but vary in their state of reduction, the single carbon moiety they bear and/or the length of the glutamate chain. At least 50% of whole body folate is stored in the liver. The influence of intracellular folate concentration depends largely on dietary intake. The supply of folate depends primarily on the quantity and bioavailability of ingested folate and the rate of loss by urinary and fecal routes and through catabolism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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