Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
| Autor: | Ayush Jain, Rakesh K. Jain, Ghisulal M. Choudhary, Gautam Prakash, GN Gupta, Aditya Nanasaheb Patil |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Wound site
medicine.medical_specialty integumentary system business.industry medicine.medical_treatment skin grafting platelet-rich plasma Hematology Surgery Platelet-rich plasma Wound Epithelialization Immunology and Allergy Medicine Skin grafting Original Article skin graft donor site dressing Diseases of the blood and blood-forming organs RC633-647.5 Hospital service business Graft donor |
| Zdroj: | Asian Journal of Transfusion Science, Vol 15, Iss 2, Pp 195-198 (2021) Asian Journal of Transfusion Science |
| ISSN: | 1998-3565 0973-6247 |
| Popis: | INTRODUCTION: The split-thickness skin graft harvested donor site is associated with prolonged healing, discomfort, and pain. Platelet-rich plasma (PRP) contains platelet-derived growth factors and has been widely used in chronic wounds and skin graft donor sites. PRP application is known to accelerate wound epithelialization rates, and also reduce postoperative wound site pain. MATERIALS AND METHODS: We assessed 20 patients admitted to our hospital service who underwent split-thickness skin grafting (STSGs) with proximal half of the donor site treated with PRP. The dressing was conducted on postoperative day 7, 14, and 21. The donor site healing was assessed with serial photographs and donor site pain measured by numerical rating scale. RESULTS: Complete healing of wounds (epithelialization) was present in 12 (60%) patients dressed with PRP. Pain on opening dressing was an average of 3.5 in PRP dressed wounds and 6.35 in control wounds. Patients dressed without PRP, none of them had complete epithelialization. All patients had partial healing and were less than the donor site dressed with PRP. Based on these results, skin graft donor site with PRP showed accelerated healing and reduced pain and discomfort compared to control without PRP. CONCLUSION: PRP is a beneficial adjunct for reducing donor site pain and increased healing of donor site following STSG harvest. |
| Databáze: | OpenAIRE |
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