Subsurface ablation of atherosclerotic plaque using ultrafast laser pulses
| Autor: | Stéphane Cook, Thomas Lanvin, Donald B. Conkey, Jérémy Valentin, Aurélien Frobert, Marie-Noëlle Giraud, Demetri Psaltis, Jean-Jacques Goy |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Materials science
medicine.diagnostic_test business.industry Plaque removal medicine.medical_treatment technology industry and agriculture Nanotechnology Laser Ablation Atomic and Molecular Physics and Optics Article law.invention Optics Optical coherence tomography law biological sciences Filament propagation medicine Pulse energy business Ultrashort pulse Hole size Biotechnology |
| Popis: | We perform subsurface ablation of atherosclerotic plaque using ultrafast pulses. Excised mouse aortas containing atherosclerotic plaque were ablated with ultrafast near-infrared (NIR) laser pulses. Optical coherence tomography (OCT) was used to observe the ablation result, while the physical damage was inspected in histological sections. We characterize the effects of incident pulse energy on surface damage, ablation hole size, and filament propagation. We find that it is possible to ablate plaque just below the surface without causing surface damage, which motivates further investigation of ultrafast ablation for subsurface atherosclerotic plaque removal. (C)2015 Optical Society of America |
| Databáze: | OpenAIRE |
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