Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice
| Autor: | Mehnaz Kamal, Mamuna Naz, Majid Ahmad Ganaie, Mohd Nazam Ansari, Amani S. Awaad, Najeeb U. Rehman, Saleh I. Alqasoumi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Pharmacology Lungs tissues animal structures 010604 marine biology & hydrobiology fungi lcsh:RM1-950 Pharmaceutical Science Health related 010501 environmental sciences Biology Allethrins 01 natural sciences Article Subchronic toxicity chemistry.chemical_compound lcsh:Therapeutics. Pharmacology chemistry Body organs Toxicity 0105 earth and related environmental sciences |
| Zdroj: | Saudi Pharmaceutical Journal, Vol 27, Iss 3, Pp 348-353 (2019) |
| ISSN: | 1319-0164 |
| Popis: | The aim of the current study was to evaluate and compare the toxicities of different types of mosquito repellents i.e. coils, mats and liquid vapors in animal models. Different types of mosquito repellents including liquid vaporizers, coils and mats have been extensively used by the people to get protection from the mosquitoes and diseases associated with them. The active constituents of these repellents include; allethrins, pyrethrins, paraffin and various other derivatives, are well known for their toxicities. Exposure of albino mice to these repellents for 3 h per day over a period of 20 days produced significant toxicological effects on vital body organs including; liver, lungs, kidneys, brain and heart. The order of toxicity of different repellents on nervous and hepatic tissues was found to be: Coil > Liquid > Mat while in renal and cardiac tissues, the coil was again found to be the most toxic one, mat with medium toxicity whereas liquid as least toxic (Coil > Mat > liquid). Lungs tissues are almost equally affected by all the repellants. On the basis of current findings, it has been concluded that exposure to various types of mosquito repellents can be deleterious to health and can cause various health related issues by producing pathological changes in the vital organs. Keywords: Allethrin, Mosquito repellents, Subchronic toxicity, Vital organs, Mice |
| Databáze: | OpenAIRE |
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