Quantitative first pass perfusion in cardiovascular magnetic resonance for determination of peak ventricular transit time—A technique for evaluation of heart function
| Autor: | Christian Jung, J. P. Heyne, Andreas Hansch, Gunter Wolf, Alexander Pfeil |
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| Rok vydání: | 2012 |
| Předmět: |
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Cardiac function curve medicine.medical_specialty Cardiac output Magnetic Resonance Imaging Cine Sensitivity and Specificity Ventricular Dysfunction Left Cardiac magnetic resonance imaging Internal medicine Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging End-systolic volume Ejection fraction medicine.diagnostic_test business.industry Myocardial Perfusion Imaging Reproducibility of Results Stroke Volume General Medicine Stroke volume Middle Aged Image Enhancement medicine.anatomical_structure Ventricle cardiovascular system Cardiology End-diastolic volume Female business Magnetic Resonance Angiography |
| Zdroj: | European Journal of Radiology. 81:e996-e1001 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2012.07.011 |
| Popis: | The aim of this study was to determine peak ventricular transit time (PVTT) using cardiac magnetic resonance (cMRI) imaging with first-pass perfusion and to evaluate PVTT as a potential new predictor of cardiac failure.cMRI was performed on 150 patients. The PVTT between the right and left ventricle was measured. Patients were divided into three groups based on their pump function: (1) severely reduced pump function (left ventricular ejection fraction, LVEF30%), (2) moderately reduced pump function (left ventricular ejection fraction, LVEF 30-54%), and (3) normal pump function (LVEF55%). PVTT from the right to left ventricle was significantly prolonged in patients with a reduced LVEF compared to the group with a normal pump function. The longest PVTT (13.4±4.8 s) was measured in patients with a severely reduced pump function, prolonged PVTT was also found in the group with moderately reduced pump function (8.5±2.1 s). The shortest PVTT (6.3±1.8 s) was observed in the group with a normal pump function. Additionally, a highly significant negative correlation was revealed between PVTT and LVEF (r=-0.696, p0.01). PVTT presented a positive significant correlation to end diastolic volume (EDV, r=0.572, p0.01) and to end systolic volume (ESV, r=0.666, p0.01).Peak ventricular transit times measured by cMRI may be an additional and simple tool to evaluate cardiac function in patients, independent of the other common cardiac functional parameters. |
| Databáze: | OpenAIRE |
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