Random drug excess
| Autor: | U Helfenstein, M Steiner |
|---|---|
| Přispěvatelé: | University of Zurich, Helfenstein, Ulrich |
| Rok vydání: | 1990 |
| Předmět: |
Drug
Time Factors Randomization media_common.quotation_subject Monte Carlo method 610 Medicine & health Multiple dose Models Biological Drug Administration Schedule Statistics Humans 2736 Pharmacology (medical) Medicine Pharmacology (medical) media_common Pharmacology business.industry Stochastic process 10060 Epidemiology Biostatistics and Prevention Institute (EBPI) Human physiology Computer experiment 3004 Pharmacology Pharmaceutical Preparations Drug intoxication business Monte Carlo Method |
| Zdroj: | European Journal of Drug Metabolism and Pharmacokinetics. 15:309-315 |
| ISSN: | 2107-0180 0378-7966 |
| DOI: | 10.1007/bf03190220 |
| Popis: | If a patient is treated in a hospital, drugs are administered at 'deterministic', known times. However, if the patient is not supervised the times of drug intake may be less 'deterministic' and less well known. It seems therefore worthwhile to make a theoretical experiment in which one assumes that drugs are applied according to a random process. In the present article it is proposed that shot noise models could be used to represent concentration curves in such situations. By means of Monte Carlo methods different measures of random drug excess are described. An included program may encourage readers to consider these methods and to perform computer experiments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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