| Autor: |
Antonello, Giulia, Marucco, Arianna, Gazzano, Elena, Kainourgios, Panagiotis, Ravagli, Costanza, Gonzalez-Paredes, Ana, Sprio, Simone, Padín-González, Esperanza, Soliman, Mahmoud G., Beal, David, Barbero, Francesco, Gasco, Paolo, Baldi, Giovanni, Carriere, Marie, Monopoli, Marco P., Charitidis, Costas A., Bergamaschi, Enrico, Fenoglio, Ivana, Riganti, Chiara |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.20341736.v1 |
| Popis: |
Additional file 1. Figure S1. Optical appearance of the colloidal suspensions before A) and after B) treatment with the SHDS. Figure S2. Size distribution of the samples directly incubated in SIF or after complete SHDS-treatment of A) LSNPs; B) CNPs, C) FNPs; D) HNPs. Figure S3. HNPs dissolution. Figure S4. Degradation of LSNPs by lipase. Table S1. Mean dH and PDI of NMs in DMEM+10% FBS (100 mg/ml), 24 h incubation. Figure S5. Aspect of the suspension of the (*) untreated and (**) SHDS-treated A) LSNPs, B) CNPs, C) FNPs and D) HNPs in cell medium. Figure S6. SDS-PAGE analysis showing the hard corona of (*) SHDS-treated and (**) untreated A) LSNPs, B) CNPs, C) FNPs and D) HNPs in cell medium and obtained by centrifugation, and E) ctrl without NBMs. Figure S7. LFQ intensity for different proteases inhibitor for FNPs untreated and SHDS-treated. Figure S8. Cells viability of A) Caco-2 cells and B) HCoEpiC cells after 24 h of incubation with SHDS fluids. Figure S9. Genotoxicity of HCT116 cells after 24 h of incubation with untreated and SHDS-treated NMs. Table S2. Tran-Epithelial Electrical Resistance (TEER) values of Caco-2 barrier model after 24 h of incubation. Figure S10. Scheme of representative SDHS treatment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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