The Extrusion of Sodium Ions from Presynaptic Nerve Endings of Rat Cerebral Cortex
| Autor: | J. G. Logan |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Male
Sodium ATPase chemistry.chemical_element Stimulation Biochemistry Ion Norepinephrine Cellular and Molecular Neuroscience Adenosine Triphosphate Presynaptic Nerve Endings medicine Animals Cerebral Cortex biology Cations Monovalent Rats medicine.anatomical_structure chemistry Cerebral cortex Biophysics biology.protein Extrusion Efflux Sodium-Potassium-Exchanging ATPase Synaptosomes |
| Zdroj: | Journal of Neurochemistry. 35:349-353 |
| ISSN: | 1471-4159 0022-3042 |
| DOI: | 10.1111/j.1471-4159.1980.tb06271.x |
| Popis: | (Na+-K+) ATPase is present in synaptosomal preparations and it is assumed to represent the sodium-potassium pump. 10 microM-noradrenaline activates (Na+-K+) ATPase approximately 100%, but 50 microM-noradrenaline does not stimulate the rate of 22Na extrusion from synaptosomes. The results suggest that it is unlikely that the noradrenaline stimulation of (Na+-K+) ATPase is part of a feedback mechanism whereby released noradrenaline can influence the activity of the presynaptic sodium pump. |
| Databáze: | OpenAIRE |
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