C–H Insertion in Dirhodium Tetracarboxylate-Catalyzed Reactions despite Dynamical Tendencies toward Fragmentation: Implications for Reaction Efficiency and Catalyst Design

Autor:	Wentao Guo, Stephanie R. Hare, Shu-Sen Chen, Carla M. Saunders, Dean J. Tantillo
Rok vydání:	2022
Předmět:	Lactones Colloid and Surface Chemistry Organometallic Compounds Rhodium General Chemistry Ketones Biochemistry Catalysis
Zdroj:	Journal of the American Chemical Society. 144:17219-17231
ISSN:	1520-5126 0002-7863
DOI:	10.1021/jacs.2c07681
Popis:	Rh-catalyzed C-H insertion reactions to form β-lactones suffer from post-transition state bifurcations, with the same transition states leading to ketones and ketenes via fragmentation in addition to β-lactones. In such a circumstance, traditional transition state theory cannot predict product selectivity, so we employed
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817753a6e5c0d50d114b7aa326b9ab28 https://doi.org/10.1021/jacs.2c07681 Zobrazit plný text záznamu