In assisted reproduction by IVF or ICSI, the rate at which embryos develop to the blastocyst stage is influenced by the fertilization method used: a split IVF/ICSI study

Autor: B. E. Speyer, Paul Serhal, Matthew Gaunt, Srividya Seshadri, Suzanne Cawood, Carleen Heath, Helen M. K. O'Neill, Wael Saab
Rok vydání: 2018
Předmět:
0301 basic medicine
Male
Pregnancy Rate
medicine.medical_treatment
Embryo development
Intracytoplasmic sperm injection
0302 clinical medicine
Human fertilization
Pregnancy
Assisted Reproduction Technologies
Genetics (clinical)
reproductive and urinary physiology
media_common
030219 obstetrics & reproductive medicine
Obstetrics and Gynecology
Embryo
General Medicine
Spermatozoa
medicine.anatomical_structure
IVF
embryonic structures
Sperm Motility
Female
Reproduction
Live Birth
Infertility
Adult
Reproductive Techniques
Assisted
media_common.quotation_subject
Embryonic Development
Fertilization in Vitro
Biology
ICSI
Andrology
03 medical and health sciences
Genetics
medicine
Humans
Blastocyst
Sperm Injections
Intracytoplasmic
In vitro fertilisation
urogenital system
medicine.disease
Embryo Transfer
Sperm
030104 developmental biology
Reproductive Medicine
Oocytes
Developmental Biology
Zdroj: Journal of Assisted Reproduction and Genetics
ISSN: 1573-7330
Popis: Purpose To compare in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) in regard to post-fertilization development and outcome with the purpose of ascertaining the most effective fertilization method for assisted reproduction. Methods A retrospective cohort study of 136 split IVF/ICSI cycles (where sibling oocytes are fertilized by two different methods using the same sperm sample). Results IVF-derived embryos developed to the blastocyst stage at a significantly faster rate than ICSI-derived embryos. There was no significant difference in fertilization or livebirth rates between the two fertilization methods. Conclusions For patients with sperm progressive motility ≥ 1.0 × 106/ml (who usually constitute the majority of patients), no significant difference between the two fertilization methods was found in regard to fertilization rate or livebirth rate. Remaining factors influencing choice between the two methods appear to be restricted to convenience, financial considerations and concern with regard to possible perpetuation of genetically linked infertility to future generations.
Databáze: OpenAIRE
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