Hemophagocytic syndrome complicating cardiac transplantation
| Autor: | Bruce F. Burns, Ross A. Davies, Francois Auclair, Jan Bormanis, Virginia M. Walley |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Pediatrics business.industry medicine.medical_treatment Fulminant Antemortem Diagnosis Immunosuppression General Medicine Pathology and Forensic Medicine Serology Transplantation Pediatric patient Shock (circulatory) medicine medicine.symptom Cardiology and Cardiovascular Medicine business Pediatric population |
| Zdroj: | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 7(1) |
| ISSN: | 1054-8807 |
| Popis: | Infection-associated hemophagocytic syndrome is one of the hemophagocytic disorders, and is most often seen in the pediatric population, typically in the setting of immunosuppression. We present the case of a 33-year-old man who had been well for more than 3 years following cardiac transplantation until he developed the infection-associated hemophagocytic syndrome. The patient had a fulminant downhill course, dying in shock 10 weeks after his first presentation. Serologic studies for Epstein-Barr virus suggested a remote infection; other viral and microbiologic studies were negative. The only previous report of infection-associated hemophagocytic syndrome complicating cardiac transplant appears to be that of a pediatric patient. The case presented illustrates the difficulties in antemortem diagnosis of this disorder, and in its treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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