Rare Case of Anal Canal Signet Ring Cell Carcinoma Associated with Perianal and Vulvar Pagetoid Spread
| Autor: | Jeong-Heum Baek, Na Rae Kim, Sung Won Park, Kyu Chan Lee, Hyun Yee Cho, Jae Yeon Seok, Dong Hae Chung, Seung Yeon Ha, Juhyeon Jeong, Sun Jin Sym |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Histology Carcinoma signet ring cell Physical examination Pathology and Forensic Medicine Metastasis Lesion 03 medical and health sciences 0302 clinical medicine Signet ring cell carcinoma medicine lcsh:Pathology medicine.diagnostic_test Case Study business.industry Signet ring cell Paget disease extramammary Anal canal medicine.disease Dissection medicine.anatomical_structure 030220 oncology & carcinogenesis Pagetoid 030211 gastroenterology & hepatology Radiology medicine.symptom business lcsh:RB1-214 |
| Zdroj: | Journal of Pathology and Translational Medicine, Vol 50, Iss 3, Pp 231-237 (2016) Journal of Pathology and Translational Medicine |
| ISSN: | 2383-7845 2383-7837 |
| Popis: | A 61-year-old woman was referred to surgery for incidentally found colonic polyps during a health examination. Physical examination revealed widespread eczematous skin lesion without pruritus in the perianal and vulvar area. Abdominopelvic computed tomography showed an approximately 4-cm-sized, soft tissue lesion in the right perianal area. Inguinal lymph node dissection and Mils' operation extended to perianal and perivulvar skin was performed. Histologically, the anal canal lesion was composed of mucin-containing signet ring cells, which were similar to those found in Pagetoid skin lesions. It was diagnosed as an anal canal signet ring cell carcinoma (SRCC) with perianal and vulvar Pagetoid spread and bilateral inguinal lymph node metastasis. Anal canal SRCC is rare, and the current case is the third reported case in the English literature. Seven additional cases were retrieved from the world literature. Here, we describe this rare case of anal canal SRCC with perianal Pagetoid spread and provide a literature review. |
| Databáze: | OpenAIRE |
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