Convection-Enhanced Delivery in the Treatment of Glioblastoma
| Autor: | Mark P. Johnson, Cindy Southerland, Susanne Jacobs, Casey B. Brown, Stevie Threatt |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Drug medicine.medical_specialty media_common.quotation_subject Antineoplastic Agents Convection 03 medical and health sciences Drug dependent Drug Delivery Systems 0302 clinical medicine Symptom relief medicine Humans Intensive care medicine Aged media_common Aged 80 and over Nursing practice Brain Neoplasms Oncology (nursing) business.industry Oncology Nursing Middle Aged medicine.disease 030220 oncology & carcinogenesis Drug delivery Female Glioblastoma Convection-Enhanced Delivery business 030217 neurology & neurosurgery |
| Zdroj: | Seminars in Oncology Nursing. 34:494-500 |
| ISSN: | 0749-2081 |
| DOI: | 10.1016/j.soncn.2018.10.004 |
| Popis: | Objective To describe the indications for convection-enhanced delivery in the treatment of glioblastoma, highlighting candidates for the delivery method, mechanics of drug delivery, and management of acute and long-term complications. Data Sources A conceptual framework drawn from published literature as well as author's expert experiences. Conclusion Convection-enhanced delivery is an established method of delivering new therapies to patients with glioblastoma. Management of both acute and long-term complications is often drug dependent. Implications for Nursing Practice Nurses should be able to recognize and manage potential complications during the infusion of agents delivered via convection-enhanced delivery. Post-infusion symptoms may worsen because of immunologic responses related to the drug and management should be directed toward symptom relief and support without interference on the immunologic response. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect