Fungi, fungicide discovery and global food security

Autor: Sarah J. Gurr, Gero Steinberg
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Fungal Genetics and Biology, 144. Academic Press Inc.
Fungal Genetics and Biology
ISSN: 1087-1845
Popis: Highlights • Fungi pose the greatest biotic challenge to global food security. • Monocultures are ideal fungal pathogen feeding and breeding grounds. • Single target site fungicides are our best “defence”, but resistance has emerged. • We need new fungicides to out-compete the pathogens in the “arms race”. • Academic and industrial collaboration could help fungicide discovery.
Securing sufficient food for a growing world population is of paramount importance for social stability and the well-being of mankind. Recently, it has become evident that fungal pathogens pose the greatest biotic challenge to our calorie crops. Moreover, the loss of commodity crops to fungal disease destabilises the economies of developing nations, thereby increasing the dimension of the threat. Our best weapon to control these pathogens is fungicides, but increasing resistance puts us in an arms race against them. New anti-fungal compounds need to be discovered, such as mono-alky lipophilic cations (MALCs) described herein. Collaborations between academia and industry are imperative to establish new and efficient ways to develop these new fungicides and to bring them to the market-place.
Databáze: OpenAIRE