Oral administration of the AYA strain of Lactobacillus plantarum modulates expression of immunity-related genes in the murine Peyer's patch: a DNA microarray analysis
| Autor: | Shin-ichi Fukudome, Keiko Abe, Tsudoi Toyoda, Tomoko Ishijima, Yuji Nakai, Yosuke Kikuchi |
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| Rok vydání: | 2014 |
| Předmět: |
Administration
Oral Biology Applied Microbiology and Biotechnology Biochemistry Analytical Chemistry Transcriptome Mice Peyer's Patches Immune system Downregulation and upregulation medicine Animals Molecular Biology Gene Microarray analysis techniques Probiotics Organic Chemistry Peyer's patch General Medicine biology.organism_classification Microarray Analysis Molecular biology medicine.anatomical_structure Gene Expression Regulation Dietary Supplements DNA microarray Lactobacillus plantarum Biotechnology |
| Zdroj: | Bioscience, biotechnology, and biochemistry. 78(11) |
| ISSN: | 1347-6947 |
| Popis: | We performed comprehensive transcriptome analysis of Peyer’s patches to elucidate the effects of oral administration of Lactobacillus plantarum strain AYA in mice. Using microarray analysis, we identified 124 upregulated and 144 downregulated genes for four weeks after the start of dietary supplementation with AYA. Gene Ontology analysis revealed that the genes for immune function were enriched in the upregulated gene set. |
| Databáze: | OpenAIRE |
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