Liver graft outcomes from donors with vaccine induced thrombosis and thrombocytopenia (VITT): United Kingdom multicenter experience

Autor:	Andreas Prachalias, Khalid Sharif, Rebecca Sanabria-Mateos, Katherine Quist, Darius F. Mirza, Owen L. Cain, Will Lester, John Forsythe, Hermien Hartog, Angus Hann, Phillip L R Nicolson, Ines Ushiro-Lumb, Anisa Nutu, George H.B. Greenhall, Douglas Thorburn, John Isaac, Ye Htun Oo, Abhishek Chauhan, M. Thamara P. R. Perera, Desley Neil, Joerg M. Pollok
Rok vydání:	2022
Předmět:	medicine.medical_specialty Tissue and Organ Procurement Lymphocyte medicine.medical_treatment Liver transplantation medicine.disease_cause Gastroenterology Autoimmunity Internal medicine medicine Humans Immunology and Allergy Pharmacology (medical) Platelet Vein Vaccines Transplantation biology business.industry Graft Survival Thrombosis medicine.disease Thrombocytopenia Tissue Donors medicine.anatomical_structure Liver biology.protein Antibody business Platelet factor 4
Zdroj:	American Journal of Transplantation. 22:996-998
ISSN:	1600-6135
Popis:	Vaccine-induced immune thrombosis and thrombocytopenia (VITT) syndrome is a new entity, characterised by severe thrombocytopenia and multiple sites of thrombosis1 . The presumed mechanism is driven by anti-platelet factor 4 (PF4) antibodies causing platelet activation1 . Donors with VITT syndrome have a particular relevance for liver transplantation (LT), due to the associated risk of passenger lymphocyte syndrome, and a predisposition for porto-mesenteric or hepatic vein thrombosis2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815b4eed23b1c4d8e5905fd94a0a083e https://doi.org/10.1111/ajt.16869 Zobrazit plný text záznamu Plný text