Synthesis of selenocysteine and selenomethionine derivatives from sulfur-containing amino acids

Se modification (i.e., the chemical atomic mutation) would be a useful approach to peptide synthesis involving selenoamino acid residues. -->
ISSN: 1612-1880
Přístupová URL adresa: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815ad679103ef4ab388e739b3fe8ea1d
https://pubmed.ncbi.nlm.nih.gov/18357559
Rights: CLOSED
Přírůstkové číslo: edsair.doi.dedup.....815ad679103ef4ab388e739b3fe8ea1d
Autor: Ryuta Ooka, Sadahiro Oishi, Michio Iwaoka, Toshifumi Nakazato, Sari Yoshida
Rok vydání: 2008
Předmět:
Zdroj: Chemistrybiodiversity. 5(3)
ISSN: 1612-1880
Popis: Selenium-containing amino acids have attracted increasing interest from view points of the importance as active centers of several selenoenzymes, the biological synthesis, the metabolism, and the use for structure determination of proteins. In this article, our recent progresses in the transformation from sulfur-containing amino acids to selenocysteine (SeCys) and selenomethionine (SeMet) derivatives are reviewed along with the surveys of general organic methodologies for the synthesis of SeCys and SeMet derivatives in the literature. The S-->Se modification (i.e., the chemical atomic mutation) would be a useful approach to peptide synthesis involving selenoamino acid residues.
Databáze: OpenAIRE