Synthesis of selenocysteine and selenomethionine derivatives from sulfur-containing amino acids
ISSN: | 1612-1880 |
---|---|
Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815ad679103ef4ab388e739b3fe8ea1d https://pubmed.ncbi.nlm.nih.gov/18357559 |
Rights: | CLOSED |
Přírůstkové číslo: | edsair.doi.dedup.....815ad679103ef4ab388e739b3fe8ea1d |
Autor: | Ryuta Ooka, Sadahiro Oishi, Michio Iwaoka, Toshifumi Nakazato, Sari Yoshida |
Rok vydání: | 2008 |
Předmět: |
chemistry.chemical_classification
Methionine Selenocysteine Stereochemistry Halogenation chemistry.chemical_element Bioengineering General Chemistry General Medicine Metabolism Biochemistry Amino acid chemistry.chemical_compound chemistry Peptide synthesis Molecular Medicine Cysteine Peptides Selenomethionine Molecular Biology Selenium |
Zdroj: | Chemistrybiodiversity. 5(3) |
ISSN: | 1612-1880 |
Popis: | Selenium-containing amino acids have attracted increasing interest from view points of the importance as active centers of several selenoenzymes, the biological synthesis, the metabolism, and the use for structure determination of proteins. In this article, our recent progresses in the transformation from sulfur-containing amino acids to selenocysteine (SeCys) and selenomethionine (SeMet) derivatives are reviewed along with the surveys of general organic methodologies for the synthesis of SeCys and SeMet derivatives in the literature. The S-->Se modification (i.e., the chemical atomic mutation) would be a useful approach to peptide synthesis involving selenoamino acid residues. |
Databáze: | OpenAIRE |
Externí odkaz: |