Methodological overview of systematic reviews to establish the evidence base for emergency general surgery

Autor: Sanjeeva Kariyawasam, Katy A Chalmers, James Chrichton, Ceri Rowlands, Natalie S Blencowe, Sean Strong, Sarah K Richards, John Mason, Daniel Stevens, Laura Gould, Victoria Pegna, Jane M Blazeby, Katie Whale, Jelena Savović, Noah Howes
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: The British Journal of Surgery
Savović, J, Blencowe, N, Strong, S, Howes, N, Chalmers, K, Chrichton, J, Gould, L, Kariyawasam, S, Mason, J, Pegna, V, Richards, S, Rowlands, C, Stevens, D, Whale, K & Blazeby, J 2017, ' Methodological overview of systematic reviews to establish the evidence base for emergency general surgery ', British Journal of Surgery, vol. 104, no. 5, pp. 513-524 . https://doi.org/10.1002/bjs.10476
ISSN: 1365-2168
0007-1323
DOI: 10.1002/bjs.10476
Popis: Background The evidence for treatment decision‐making in emergency general surgery has not been summarized previously. The aim of this overview was to review the quantity and quality of systematic review evidence for the most common emergency surgical conditions. Methods Systematic reviews of the most common conditions requiring unplanned admission and treatment managed by general surgeons were eligible for inclusion. The Centre for Reviews and Dissemination databases were searched to April 2014. The number and type (randomized or non‐randomized) of included studies and patients were extracted and summarized. The total number of unique studies was recorded for each condition. The nature of the interventions (surgical, non‐surgical invasive or non‐invasive) was documented. The quality of reviews was assessed using the AMSTAR checklist. Results The 106 included reviews focused mainly on bowel conditions (42), appendicitis (40) and gallstone disease (17). Fifty‐one (48·1 per cent) included RCTs alone, 79 (74·5 per cent) included at least one RCT and 25 (23·6 per cent) summarized non‐randomized evidence alone. Reviews included 727 unique studies, of which 30·3 per cent were RCTs. Sixty‐five reviews compared different types of surgical intervention and 27 summarized trials of surgical versus non‐surgical interventions. Fifty‐seven reviews (53·8 per cent) were rated as low risk of bias. Conclusion This overview of reviews highlights the need for more and better research in this field.
Evidence still limited
Databáze: OpenAIRE
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