Autor: |
Yukiko Hoshino, Masaki Takechi, Mehran Moazen, Miranda Steacy, Daisuke Koyabu, Toshiko Furutera, Youichirou Ninomiya, Takashi Nuri, Erwin Pauws, Sachiko Iseki |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Journal of anatomyREFERENCES. |
ISSN: |
1469-7580 |
Popis: |
Syndromic craniosynostosis (CS) patients exhibit early, bony fusion of calvarial sutures and cranial synchondroses, resulting in craniofacial dysmorphology. In this study, we chronologically evaluated skull morphology change after abnormal fusion of the sutures and synchondroses in mouse models of syndromic CS for further understanding of the disease. We found fusion of the inter-sphenoid synchondrosis (ISS) in Apert syndrome model mice (Fgfr2 |
Databáze: |
OpenAIRE |
Externí odkaz: |
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