Foetal bovine intermuscular adipose tissue exhibits histological and metabolic features of brown and white adipocytes during the last third of pregnancy
| Autor: | Maria Cristina Zingaretti, Yves Chilliard, H. Taga, Muriel Bonnet, Brigitte Picard |
|---|---|
| Přispěvatelé: | Unité Mixte de Recherche sur les Herbivores - UMR 1213 (UMRH), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de la Recherche Agronomique (INRA)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Università Politecnica delle Marche, Partenaires INRAE |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Leptin
medicine.medical_specialty Adipose Tissue White Adipose tissue Glycerolphosphate Dehydrogenase White adipose tissue Biology Glucosephosphate Dehydrogenase SF1-1100 03 medical and health sciences chemistry.chemical_compound Adipose Tissue Brown BREEDS Malate Dehydrogenase Pregnancy Adipocyte Internal medicine medicine Adipocytes Animals RNA Messenger Muscle Skeletal 030304 developmental biology 2. Zero hunger LIPID METABOLISM 0303 health sciences Lipoprotein lipase Adiponectin 0402 animal and dairy science 04 agricultural and veterinary sciences INTERMUSCULAR ADIPOSE TISSUE BOVINE FOETUS 040201 dairy & animal science Breed Thermogenin Animal culture Endocrinology chemistry Adipose Tissue [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies embryonic structures MORPHOLOGY Animal Science and Zoology Cattle Female Fatty Acid Synthases |
| Zdroj: | animal animal, Published by Elsevier (since 2021) / Cambridge University Press (until 2020), 2012, 6 (4), pp.641-649. ⟨10.1017/S1751731111001716⟩ Animal Animal, Published by Elsevier (since 2021) / Cambridge University Press (until 2020), 2012, 6 (4), pp.641-649. ⟨10.1017/S1751731111001716⟩ Animal, Vol 6, Iss 4, Pp 641-649 (2012) |
| ISSN: | 1751-7311 1751-732X |
| Popis: | International audience; This study reports the metabolic and morphological characteristics of bovine intermuscular adipose tissue (AT) throughout foetal growth. Our hypothesis was that the histological and molecular features of intermuscular AT would be different from those previously reported for foetal perirenal AT, based on its anatomical location near the muscle and the recent identification of two distinct adipocyte precursors in mouse AT depending on their locations. To address this question, intermuscular AT was sampled from Charolais and Blond d’Aquitaine foetuses at 180, 210 and 260 days post conception (dpc). The two bovine breeds were chosen because of the higher adiposity of Charolais than Blond d’Aquitaine cattle during the postnatal life. Regardless of the breed, adipocyte volume increased slightly (138%, P,0.01) with increasing foetal age. This was concomitant with a decrease ( P,0.05) in the activity of enzymes involved in de novo fatty acid (FA) synthesis (FA synthase and glucose-6-phosphate dehydrogenase) and FA esterification (glycerol-3-phosphate dehydrogenase) when expressed per million adipocytes, and with an increase ( P |
| Databáze: | OpenAIRE |
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