Myocardial Depression During Diplococcus pneumoniae Infection in Monkeys
| Autor: | J. H. Boucher, C. T. Liu, D. E. Hilmas, R. O. Spertzel, W. P. Czajkowski |
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| Rok vydání: | 1974 |
| Předmět: |
Hyperthermia
Tachycardia Cardiac Volume Heart Ventricles Blood Pressure Pneumococcal Infections General Biochemistry Genetics and Molecular Biology Body Temperature Contractility Heart Rate Sepsis Heart rate Animals Medicine Statistical analysis Cardiac Output business.industry Heart Haplorhini medicine.disease Myocardial depression Streptococcus pneumoniae Anesthesia Bacteremia Diplococcus pneumoniae Macaca medicine.symptom business |
| Zdroj: | Experimental Biology and Medicine. 145:112-116 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-145-37759 |
| Popis: | SummaryThis report describes the extent to which 108D. pneumoniae organisms, administered iv, caused changes in heart rate, body temperature, and myocardial contractility in five of six conscious, chair-restrained mature rhesus monkeys. Within 16 hr after pneumococcal infection, hyperthermia, tachycardia, and decreased cardiac contractility were observed. All parameters returned to relatively normal levels 4 days postinfection. It is unknown why myocardial depression occurred coincident with febrile response and tachycardia.We gratefully acknowledge the technical assistance of Robert Baker, Keith Bond, and Steve Kinzer. Gratitude is also expressed to Dr. Alan Rowberg for statistical analysis, Mrs. Phebe Summers for medical illustrations, Mr. Wallace Fee for providing cultured organisms, and Mr. Dennis Leatherman for bacteremia analysis. |
| Databáze: | OpenAIRE |
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