Neonatal brain injury influences structural connectivity and childhood functional outcomes

Autor:	Alice Ramirez, Shabnam Peyvandi, Stephany Cox, Dawn Gano, Duan Xu, Olga Tymofiyeva, Patrick S. McQuillen
Přispěvatelé:	Duerden, Emma
Rok vydání:	2021
Předmět:	Central Nervous System Male Social Sciences Cardiovascular Medicine Cardiovascular Nervous System Diagnostic Radiology Congenital Medical Conditions Infant Mortality Neural Pathways Medicine and Health Sciences Morphogenesis 2.1 Biological and endogenous factors Psychology Brain Damage Longitudinal Studies Prospective Studies Aetiology Child Heart Defects Language Pediatric Brain Mapping Multidisciplinary Radiology and Imaging Brain Congenital Heart Defects Magnetic Resonance Imaging Heart Disease Neurology Cardiovascular Diseases Neurological Hypoxia-Ischemia Brain Medicine Female Anatomy Research Article Heart Defects Congenital Computer and Information Sciences Physical Injury - Accidents and Adverse Effects Neural Networks General Science & Technology Imaging Techniques 1.1 Normal biological development and functioning Science Cardiology Research and Analysis Methods Clinical Research Underpinning research Diagnostic Medicine Hypoxia-Ischemia Congenital Disorders Connectome Humans Birth Defects Neurosciences Cognitive Psychology Infant Newborn Infant Biology and Life Sciences Neonates Perinatal Period - Conditions Originating in Perinatal Period Connectomics Newborn Brain Disorders Neuroanatomy Diffusion Magnetic Resonance Imaging Brain Injuries Cognitive Science Nerve Net Neuroscience Developmental Biology
Zdroj:	PLoS ONE, Vol 17, Iss 1 (2022) PLoS ONE PloS one, vol 17, iss 1 PLoS ONE, Vol 17, Iss 1, p e0262310 (2022)
ISSN:	1932-6203
Popis:	Neonatal brain injury may impact brain development and lead to lifelong functional impairments. Hypoxic-ischemic encephalopathy (HIE) and congenital heart disease (CHD) are two common causes of neonatal brain injury differing in timing and mechanism. Maturation of whole-brain neural networks can be quantified during development using diffusion magnetic resonance imaging (dMRI) in combination with graph theory metrics. DMRI of 35 subjects with CHD and 62 subjects with HIE were compared to understand differences in the effects of HIE and CHD on the development of network topological parameters and functional outcomes. CHD newborns had worse 12–18 month language (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814ff638d3f3bc1619687b574a2043cd https://pubmed.ncbi.nlm.nih.gov/34986206 Zobrazit plný text záznamu