Cooking influence in tolerance acquisition in egg-induced acute food protein enterocolitis syndrome
| Autor: | Lucia Liotti, Francesca Mori, Iride Dello Iacono, S. Viola, Carla Mastrorilli, S. Miceli Sopo, Carlo Caffarelli, Simona Barni, S. Monaco, Antonino Romano, Fabrizio Franceschini, Barbara Cuomo, Salvatore Tripodi, Claudia Fantacci, G. Barilaro, D. Viggiano, G Monti, Laura Badina, Giorgio Longo, G. Bersani |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Allergy Cooking Egg Food protein induced enterocolitis syndrome Oral food challenge Tolerance acquisition Immunology and Allergy Immunology Settore MED/12 - GASTROENTEROLOGIA Egg protein Physiology 03 medical and health sciences 0302 clinical medicine Allergy test Immune Tolerance medicine Humans Ingestion Child Egg Hypersensitivity Retrospective Studies Enterocolitis business.industry Egg Proteins Syndrome General Medicine Allergens cooking egg food protein induced enterocolitis syndrome medicine.disease Food protein-induced enterocolitis syndrome Italy 030228 respiratory system Child Preschool Acute Disease embryonic structures Female Age of onset medicine.symptom business 030215 immunology |
| Popis: | Background Few studies on the age of resolution of Food Protein Induced Enterocolitis Syndrome (FPIES) induced by solid foods are available. In particular, for FPIES induced by egg, the mean age of tolerance acquisition reported in the literature ranges from 42 to 63 months. Objective We have assessed whether the age of tolerance acquisition in acute egg FPIES varies depending on whether the egg is cooked or raw. Methods We conducted a retrospective and multicentric study of children with diagnosis of acute egg FPIES seen in 10 Italian allergy units between July 2003 and October 2017. The collected data regarded sex, presence of other allergic diseases, age of onset of symptoms, kind and severity of symptoms, cooking technique of the ingested egg, outcome of the allergy test, age of tolerance acquisition. Results Sixty-one children with acute egg FPIES were enrolled, 34 (56%) males and 27 (44%) females. Tolerance to cooked egg has been demonstrated by 47/61 (77%) children at a mean age of 30.2 months. For 32 of them, tolerance to raw egg has been demonstrated at a mean age of 43.9 months. No episodes of severe adverse reaction after baked egg ingestion have been recorded. Conclusions It is possible to perform an OFC with baked egg, to verify the possible acquisition of tolerance, at about 30 months of life in children with acute egg FPIES. |
| Databáze: | OpenAIRE |
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