Adenoma Prevalence and Distribution Among US Latino Subgroups Undergoing Screening Colonoscopy
| Autor: | Katherine N. DuHamel, Pathu Sriphanlop, Cristina Villagra, Lina Jandorf, Steven H. Itzkowitz, Kristen K. Lee, Sumedha V. Chablani |
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| Rok vydání: | 2016 |
| Předmět: |
Oncology
Male Physiology Colorectal cancer Colonoscopy law.invention 0302 clinical medicine Randomized controlled trial law Neoplasms Prevalence Prospective Studies Early Detection of Cancer medicine.diagnostic_test Smoking Gastroenterology Age Factors Hispanic or Latino Emigration and Immigration Middle Aged 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female medicine.symptom Colorectal Neoplasms Adenoma medicine.medical_specialty Colonic Polyps Malignancy Asymptomatic Article 03 medical and health sciences Internal medicine medicine Humans Socioeconomic status Aged business.industry Dominican Republic Puerto Rico Hepatology medicine.disease digestive system diseases United States Cross-Sectional Studies Socioeconomic Factors business Acculturation |
| Zdroj: | Digestive diseases and sciences. 62(6) |
| ISSN: | 1573-2568 |
| Popis: | Colorectal cancer (CRC) is the second leading malignancy diagnosed among US Latinos. Latinos in the USA represent a heterogeneous amalgam of subgroups varying in genetic background, culture, and socioeconomic status. Little is known about the frequency of CRC precursor lesions found at screening colonoscopy among Latino subgroups. The aim was to determine the prevalence and distribution of histologically confirmed adenomas found at screening colonoscopy among average-risk, asymptomatic US Latinos according to their subgroup and socio-demographic background. Cross-sectional analysis of pathological findings resulting from screening colonoscopy among average-risk, asymptomatic US Latinos aged ≥50 in two prospective randomized controlled trials at an academic medical center. Among the 561 Latinos who completed screening colonoscopy, the two largest subgroups were Puerto Ricans and Dominicans. The findings among both subgroups were: adenomas 30.6%, proximal adenomas 23.5%, advanced adenomas 12.0%, and proximal advanced adenomas 8.9%. These rates are at least as high as those found at screening colonoscopy among US whites. While Puerto Ricans were more likely than Dominicans to be born in the USA, speak English, be acculturated, have a smoking history, and be obese, there were no significant differences in adenoma rates between these subgroups. The prevalence of adenomas, advanced adenomas, and proximal neoplasia was high among both subgroups. These findings have implications for CRC screening and surveillance among the increasingly growing Latino population in the USA. |
| Databáze: | OpenAIRE |
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