Quality of life in young men after radical prostatectomy
| Autor: | J L, Wright, D W, Lin, J E, Cowan, P R, Carroll, M S, Litwin, Joseph N, Macaluso |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Urology medicine.medical_treatment Logistic regression Postoperative Complications Quality of life Acquired immunodeficiency syndrome (AIDS) Surveys and Questionnaires Internal medicine medicine Humans Longitudinal Studies Aged Prostatectomy Gynecology business.industry Prostatic Neoplasms Middle Aged Urination Disorders Urinary function medicine.disease humanities Sexual Dysfunction Physiological Sexual dysfunction Oncology Conventional PCI Quality of Life medicine.symptom Sexual function business Follow-Up Studies |
| Zdroj: | Prostate Cancer and Prostatic Diseases. 11:67-73 |
| ISSN: | 1476-5608 1365-7852 |
| DOI: | 10.1038/sj.pcan.4500980 |
| Popis: | Urinary and sexual function and bother are important outcomes following radical prostatectomy (RP). Since urinary and sexual function are age-related, post-operative bother may vary by age. This study explores the disease-specific quality-of-life outcomes in young men compared with older men undergoing RP. Using CaPSURE data, we identified men who underwent RP and completed the UCLA Prostate Cancer Index (PCI) before and 1-year post-RP. Men were stratified by age (55 years, 55-64,or = 65). Multivariate regression models were created: a linear model for predictors of PCI scores and a logistic model for predictors of severe declines in PCI domains. Younger men scored significantly better than older men in urinary function (P=0.04), urinary bother (P=0.02) and sexual function (P0.0001) 1-year post-RP. Severe declines in urinary bother (odds ratio (OR)=1.54, 1.01-2.35) and sexual function (OR=3.20, 1.97-5.19) were more common in menor = 65 years. Men with relationships had less urinary bother (P=0.03) and were less likely to experience severe worsening of urinary bother (OR=0.32, 0.17-0.60) while having a greater risk of severe worsening of sexual bother (OR=2.74, 1.28-5.89). The use of sexual aids was associated with worse sexual bother (P0.0001) and greater risk of severe worsening of sexual bother (OR=2.29, 1.54-3.30). Baseline PCI scores were independent predictors in all models. One year after RP, younger men (age55) have similar, or better, urinary and sexual function and bother. Baseline scores are strongly associated with post-RP scores and severity of declines. Current relationships and use of sexual aids have significant roles in post-RP bother. |
| Databáze: | OpenAIRE |
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