Multiple daily injections in young patients using the ezy-BICC bolus insulin calculation card, compared to mixed insulin and CSII
| Autor: | Donald G Anderson |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Adolescent endocrine system diseases Cost-Benefit Analysis Injections Subcutaneous Endocrinology Diabetes and Metabolism medicine.medical_treatment Young Adult Insulin Infusion Systems Diabetes mellitus Internal Medicine medicine Humans Hypoglycemic Agents Insulin Child Injections subcutaneous Glycated Hemoglobin Meal Haemoglobin A1c business.industry Age Factors Infant Newborn Basal bolus Infant Infusion Pumps Implantable medicine.disease Surgery Subcutaneous insulin Diabetes Mellitus Type 1 Treatment Outcome Child Preschool Anesthesia Pediatrics Perinatology and Child Health Costs and Cost Analysis Female Lower cost business |
| Zdroj: | Pediatric Diabetes. 10:304-309 |
| ISSN: | 1399-5448 1399-543X |
| DOI: | 10.1111/j.1399-5448.2008.00484.x |
| Popis: | To describe the easy bolus insulin calculation card (ezy-BICC) approach to multiple daily injections and to compare in an observational study, the haemoglobin A1c (HbA1c) achieved while using ezy-BICC, mixed insulin injections and continuous subcutaneous insulin infusion (CSII).HbA1c results from 7121 clinic visits by 573 patients aged 1-20 yr using the three methods between June 2000 and July 2008 were reviewed.For mixed insulin median, mean and SD HbA1c were 8.3%, 8.3%, 1.33, for ezy-BICC, 7.6%, 7.7%, 1.40, and for CSII, 7.6%, 7.8%, 1.31. HbA1c increases with age significantly more in those using CSII (p0.001). By regression, compared with mixed insulin HbA1c is 0.7% lower using ezy-BICC (p0.018) and 1.5% lower using CSII (p0.001). For patients using CSII compared with6 yr, those 6-12 yr have HbA1c 0.7% higher (p0.001), 12-15 yr 1.0% higher (p0.001) and 15-20 yr 1.2% higher (p0.001). For subjects12 yr, HbA1c is lower while using ezy-BICC than CSII. HbA1c increases 0.2% per yr following diagnosis for 2.8 yr. In those who change from mixed insulin to ezy-BICC after this time, the mean HbA1c is 0.5% lower by 9 months, 0.7% lower at 21 months and 0.6% lower at 24 months (p0.05).The ezy-BICC system is inexpensive and convenient and allows patients to vary meal size. Subjects achieve lower HbA1c while using CSII and ezy-BICC MDI than with mixed insulin. Very young subjects achieve excellent HbA1c using CSII, but for 12 to 20 yr-old patients, ezy-BICC results in lower HbA1c than CSII for a lower cost. |
| Databáze: | OpenAIRE |
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