Factor-specific deactivation of leucocyte Chemotaxis in vivo
| Autor: | Claes Dahlgren, Olle Stendahl, Gunnar Briheim |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Meningitis Pneumococcal Neutrophils business.industry Leucocyte chemotaxis Chemotaxis Hematology Meningitis Meningococcal Blood Physiological Phenomena medicine.disease Peripheral blood N-Formylmethionine Leucyl-Phenylalanine Chemotaxis Leukocyte Cerebrospinal fluid In vivo Healthy control Immunology medicine Humans Female Bacterial meningitis business Meningitis |
| Zdroj: | Scandinavian Journal of Haematology. 37:253-258 |
| ISSN: | 0036-553X |
| Popis: | This report analyses the locomotory capacity of polymorphonuclear leucocytes (PMNL) isolated from 7 patients with bacterial meningitis. 7 healthy control subjects were also investigated in parallel. It was found that PMNL from the patients suffering from meningitis, isolated both from peripheral blood and from the cerebrospinal fluid, had lost their ability to respond chemotactically to activated serum but not to the chemotactic peptide f-Met-Leu-Phe. The normal chemotactic responsiveness of blood PMNL was restored once the patients recovered from infection. |
| Databáze: | OpenAIRE |
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