Sex differences in early and long-term results of coronary angioplasty in the NHLBI PTCA Registry
| Autor: | Eugene R. Passamani, Sheryl F. Kelsey, Michael J. Cowley, Katherine M. Detre, Andreas R. Gruentzig, Kenneth M. Kent, Suzanne M. Mullin |
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| Rok vydání: | 1985 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis medicine.medical_treatment Coronary Disease Angina Pectoris Angina Sex Factors Physiology (medical) Angioplasty Internal medicine medicine Humans Registries Myocardial infarction Coronary Artery Bypass Anthropometry Unstable angina business.industry Incidence (epidemiology) Age Factors Long term results Middle Aged medicine.disease United States Surgery Bypass surgery Evaluation Studies as Topic Cardiology Female Cardiology and Cardiovascular Medicine business Angioplasty Balloon Follow-Up Studies |
| Zdroj: | Circulation. 71:90-97 |
| ISSN: | 1524-4539 0009-7322 |
| Popis: | To assess whether gender influenced the outcome of percutaneous transluminal coronary angioplasty (PTCA), we analyzed data from the NHLBI PTCA Registry. Early results were compared in 705 women and 2374 men. Women were older (p less than .01) and had more unstable angina (p less than .01), and class 3 or 4 angina (p less than .01). Men had more multivessel disease (p less than .01), prior bypass surgery (p less than .01), and abnormal left ventricular function (p less than .05). Women had a lower angiographic success rate (60.3 vs 66.2%; p less than .01) and had a lower clinical success rate (56.6% vs 62.2%; p less than .01). More women had complications (27.2% vs 19.4%; p less than .01), but overall frequency of major complications (death, myocardial infarction, emergency surgery) was not different (9.8% vs 9.3%). Women had a higher incidence of coronary dissection (p less than .05) and higher in-hospital mortality (1.8% vs 0.7%; p less than .01). PTCA-related mortality was nearly six times higher in women (1.7% vs 0.3%; p less than .001) and mortality with emergency surgery was more than five time higher (17.4% vs 3.2%; p less than .001). Multivariate analysis indicated that female gender was an independent predictor for lower success (p less than .05) and early mortality (p less than .05) and was the only baseline predictor for PTCA-related mortality.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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