Driving following Kava Use and Road Traffic Injuries: A Population-Based Case-Control Study in Fiji (TRIP 14)

Autor: Josephine Herman, Berlin Kafoa, Shanthi Ameratunga, Bridget Kool, Iris Wainiqolo, Elizabeth Robinson, Eddie McCaig
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
lcsh:Medicine
Poison control
Social Sciences
Transportation
Criminology
Geographical Locations
0302 clinical medicine
Sociology
Risk Factors
Surveys and Questionnaires
Medicine and Health Sciences
Odds Ratio
Medicine
030212 general & internal medicine
lcsh:Science
Flowering Plants
Kava
education.field_of_study
Multidisciplinary
Alcohol Consumption
05 social sciences
Accidents
Traffic

Plants
Middle Aged
Transportation Infrastructure
Police
3. Good health
Professions
Research Design
Engineering and Technology
Grapevine
Female
Risk assessment
Research Article
Adult
Adolescent
Population
Oceania
Research and Analysis Methods
Pacific Islands
Civil Engineering
Risk Assessment
Odds
03 medical and health sciences
Young Adult
Environmental health
0502 economics and business
Injury prevention
Fiji
Humans
education
Nutrition
050210 logistics & transportation
business.industry
lcsh:R
Organisms
Biology and Life Sciences
Odds ratio
Roads
Diet
Case-Control Studies
Attributable risk
People and Places
Automotive Engineering
Multivariate Analysis
lcsh:Q
Population Groupings
Plant Preparations
business
human activities
Zdroj: PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0149719 (2016)
ISSN: 1932-6203
Popis: OBJECTIVE: To investigate the association between kava use and the risk of four-wheeled motor vehicle crashes in Fiji. Kava is a traditional beverage commonly consumed in many Pacific Island Countries. Herbal anxiolytics containing smaller doses of kava are more widely available. METHODS: Data for this population-based case-control study were collected from drivers of 'case' vehicles involved in serious injury-involved crashes (where at least one road user was killed or admitted to hospital for 12 hours or more) and 'control' vehicles representative of 'driving time' in the study base. Structured interviewer administered questionnaires collected self-reported participant data on demographic characteristics and a range of risk factors including kava use and potential confounders. Unconditional logistic regression models estimated odds ratios relating to the association between kava use and injury-involved crash risk. FINDINGS: Overall, 23% and 4% of drivers of case and control vehicles, respectively, reported consuming kava in the 12 hours prior to the crash or road survey. After controlling for assessed confounders, driving following kava use was associated with a four-fold increase in the odds of crash involvement (Odds ratio: 4.70; 95% CI: 1.90-11.63). The related population attributable risk was 18.37% (95% CI: 13.77-22.72). Acknowledging limited statistical power, we did not find a significant interaction in this association with concurrent alcohol use. CONCLUSION: In this study conducted in a setting where recreational kava consumption is common, driving following the use of kava was associated with a significant excess of serious-injury involved road crashes. The precautionary principle would suggest road safety strategies should explicitly recommend avoiding driving following kava use, particularly in communities where recreational use is common. Language: en
Databáze: OpenAIRE