Acute isolated trigeminal neuropathy following calcium hydroxylapatite‐based soft tissue filler injection: A case report
| Autor: | V. L. Golubev, O R Orlova, Elena Karpova, Leniza Rifcatovna Mingazova, Sebastian Cotofana, Stanislav Murakov |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Cosmetic Techniques Dermatology Injections Lesion 030207 dermatology & venereal diseases 03 medical and health sciences Trigeminal ganglion 0302 clinical medicine Bolus (medicine) medicine Humans Injection Procedure business.industry Soft tissue Ganglion Durapatite medicine.anatomical_structure Trigeminal Nerve Diseases 030220 oncology & carcinogenesis Anesthesia Scalp Vomiting Calcium Female medicine.symptom business |
| Zdroj: | Journal of Cosmetic Dermatology. 20:1505-1511 |
| ISSN: | 1473-2165 1473-2130 |
| Popis: | Background Soft tissue filler injections are frequently performed with a relatively low number of severe adverse events reported. While venous complications have been described, the majority of adverse events are generally associated with the arterial vascular system. Intra-arterial product application can present with pain, skin discoloration, and potential tissue loss and/or injection related visual compromise. Aim We present the clinical case and the consecutive symptomology of a 39-year-old woman injected with calcium hydroxylapatite at the zygomatic arch with five perpendicular needle (27G 12mm) supraperiosteal bolus injections of 0.2 cc per site. Methods Immediately after the injections, weakness, nausea, vomiting, and loss of consciousness occurred. Additionally, left-sided loss of sensation of her face, scalp, oral, and nasal mucosa occurred, with absence of left corneal reflex and ipsi-lateral ear congestion. Subsequently, left-sided masseteric atrophy and dysphagia occurred. Results One year after the injection procedure the sensory loss of her facial skin and scalp persisted, while the other symptoms improved. Medications involved in the symptomatic (not causal) partial recovery process were Dexamethasone, Vitamin B complex, Vinpocetine, Pentoxifyllin, and Thioctic acid. Conclusion The symptoms presented and the time-related relationship to the injection procedure increases the likeliness of an association between the administration of the calcium hydroxylapatite product and a lesion of the trigeminal ganglion. The resulting symptoms can altogether be related to the functions of the ganglion. The connecting pathway between the injection site and the ganglion can be explained by the arterial vascular pathway. |
| Databáze: | OpenAIRE |
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