Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model
Autor: | Harter, PN, Dützmann, S, Drott, U, Hattingen, E, Capper, D, Gessler, F, Senft, C, Seifert, V, Plate, KH, Kögel, D, Mittelbronn, M |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: | |
Zdroj: | 57th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN); 20120912-20120915; Erlangen; DOC12dgnnPP5.9 /20120911/ |
DOI: | 10.3205/12dgnn109 |
Popis: | In vitro and descriptive studies of human tissue samples revealed the pro-coagulant glycoprotein tissue factor (TF) as a potent player in glioma cell infiltration that is activated by hypoxia and has also been shown to be upregulated by mutations of TP53 or PTEN. In the present study, we established[for full text, please go to the a.m. URL] 57th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) |
Databáze: | OpenAIRE |
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