High hydrostatic pressure effects investigated by neutron scattering on lipid multilamellar vesicles
| Autor: | Judith Peters, Bruno Demé, Jérémie Marion, Moeava Tehei, Marcus Trapp, Thomas Gutberlet |
|---|---|
| Přispěvatelé: | Institut Laue-Langevin (ILL), ILL, ILL Grenoble, F-38042 Grenoble, France, Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA) |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Phase transition
Hydrostatic pressure Neutron diffraction Analytical chemistry General Physics and Astronomy 02 engineering and technology Neutron scattering 010402 general chemistry 01 natural sciences Phase Transition MESH: Dimyristoylphosphatidylcholine MESH: Hydrostatic Pressure Phase (matter) Hydrostatic Pressure Physical and Theoretical Chemistry Atmospheric pressure [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry Molecular Biology/Structural Biology [q-bio.BM] Scattering Chemistry Temperature 021001 nanoscience & nanotechnology MESH: Temperature 0104 chemical sciences MESH: Neutron Diffraction Neutron Diffraction Liposomes MESH: Liposomes MESH: Phase Transition 0210 nano-technology Dimyristoylphosphatidylcholine Bar (unit) |
| Zdroj: | Physical Chemistry Chemical Physics Physical Chemistry Chemical Physics, Royal Society of Chemistry, 2013, 15 (48), pp.20951-6. ⟨10.1039/c3cp52762j⟩ Physical Chemistry Chemical Physics, 2013, 15 (48), pp.20951-6. ⟨10.1039/c3cp52762j⟩ |
| ISSN: | 1463-9076 1463-9084 |
| DOI: | 10.1039/c3cp52762j⟩ |
| Popis: | International audience; The effects of high hydrostatic pressure on the structure and dynamics of model membrane systems were investigated using neutron scattering. Diffraction experiments show shifts of the pre- and main-phase transitions of multilamellar vesicles of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) to higher temperatures with increased pressure which are close to results observed previously by other techniques, namely (10.4 ± 1.0) K kbar(-1) and (20.0 ± 0.5) K kbar(-1) for the two transitions. Backscattering spectroscopy reveals that the mean square displacements in the liquid phase are about 10% smaller at 300 bar and about 20% smaller at 600 bar compared to atmospheric pressure, whereas in the gel phase below the main phase transition the mean square displacements show a smaller difference in the dynamics of the three pressure values within the studied pressure range. |
| Databáze: | OpenAIRE |
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