Maintenance Therapy With the Lowest Effective Dose of Oral Viscous Budesonide in Children With Eosinophilic Esophagitis
Autor: | Danilo Rossetti, Danila Volpe, Salvatore Oliva, Carla Giordano, Gianluca Terrin, Paola Papoff, Silvio Veraldi, Giusy Russo, Cosimo Ruggiero, Chiara Maria Trovato |
---|---|
Rok vydání: | 2022 |
Předmět: |
Budesonide
medicine.medical_specialty Dose Gastroenterology topical steroids Maintenance therapy Internal medicine medicine Humans Child Eosinophilic esophagitis Glucocorticoids maintenance treatment Hepatology business.industry Maintenance strategy Eosinophilic Esophagitis medicine.disease Effective dose (pharmacology) Eosinophilic inflammation Steroids Dose reduction eosinophilic esophagitis business medicine.drug |
Zdroj: | Clinical Gastroenterology and Hepatology. 20:2905-2907.e2 |
ISSN: | 1542-3565 |
Popis: | Eosinophilic esophagitis (EoE) is an immune-mediated condition characterized by symptoms of esophageal dysfunction and an eosinophilic inflammation of the esophagus.1 Swallowed topical steroids represent one of the possible strategies for inducing and maintaining remission in EoE.2 To date, a validated maintenance strategy has yet to be defined, especially in children. The available evidence suggests decreasing the dose after a successful induction therapy.3 No study has reported the efficacy of a continuous progressive dose reduction; thus, it is unknown if all patients need to use the same dosages and for how long.4,5. |
Databáze: | OpenAIRE |
Externí odkaz: |