Metabolic Disorders in Delirious Syndrome in Patients with Acute Poisoning with Gamma-Hydroxybutyric Acid and its Precursor
| Autor: | B. V. Batotsyrenov, A. N. Lodyagin, A. G. Sinenchenko |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: |
metabolic lactic acidosis
medicine.medical_specialty gamma-butyrolactone hyperammonemia business.industry RC86-88.9 acute poisoning gamma-Hydroxybutyric acid Medical emergencies. Critical care. Intensive care. First aid Gastroenterology Acute toxicity Internal medicine Emergency Medicine medicine gamma-hydroxybutyric acid metabolic disorders In patient business medicine.drug |
| Zdroj: | Neotložnaâ Medicinskaâ Pomoŝʹ, Vol 9, Iss 2, Pp 210-214 (2020) |
| ISSN: | 2541-8017 2223-9022 |
| Popis: | In 21 male patients aged 20 to 40 years, metabolic disorders in post-toxic delirious syndrome caused by gamma-hydroxybutyric acid poisoning and its precursors were studied. In the examined group of patients, hyperammonemia was detected in 71.4% of cases, metabolic lactic acidosis was revealed in 76.2%. The direct correlation between the severity of metabolic disorders and delirious syndrome according to DRS-R-98 scale was established. The statistically significant increase in capillary blood levels of lactate on day 3 of psychotic period was 4.9 mlmol/L and ammonia on day 5 was 187.0 mmol/L. The greatest severity of metabolic disorders was found in patients over the age of 27 years who systematically use the studied substances with narcotic effects for 7 months or more and combine their intake with other psychoactive substances. |
| Databáze: | OpenAIRE |
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