INVESTIGATION OF PARTIAL VOLUME EFFECT IN DIFFERENT PET/CT SYSTEMS: A COMPARISON OF RESULTS USING THE MADEIRA PHANTOM AND THE NEMA NU-2 2001 PHANTOM
| Autor: | Irina Zvonova, Marie Sydoff, Larisa Chipiga, Christian Bernhardsson |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Treatment response
Materials science Image quality Partial volume Single-photon emission computed tomography Sensitivity and Specificity Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Neoplasms Positron Emission Tomography Computed Tomography medicine Humans Radiology Nuclear Medicine and imaging Image resolution PET-CT Radiation Radiological and Ultrasound Technology medicine.diagnostic_test Phantoms Imaging business.industry Public Health Environmental and Occupational Health Reproducibility of Results Equipment Design General Medicine Image Enhancement Tumor Burden Equipment Failure Analysis Positron emission tomography 030220 oncology & carcinogenesis Artifacts Nuclear medicine business |
| Zdroj: | Radiation Protection Dosimetry. 169:365-370 |
| ISSN: | 1742-3406 0144-8420 |
| Popis: | Positron emission tomography combined with computed tomography (PET/CT) is a quantitative technique used for diagnosing various diseases and for monitoring treatment response for different types of tumours. However, the accuracy of the data is limited by the spatial resolution of the system. In addition, the so-called partial volume effect (PVE) causes a blurring of image structures, which in turn may cause an underestimation of activity of a structure with high-activity content. In this study, a new phantom, MADEIRA (Minimising Activity and Dose with Enhanced Image quality by Radiopharmaceutical Administrations) for activity quantification in PET and single photon emission computed tomography (SPECT) was used to investigate the influence on the PVE by lesion size and tumour-to-background activity concentration ratio (TBR) in four different PET/CT systems. These measurements were compared with data from measurements with the NEMA NU-2 2001 phantom. The results with the MADEIRA phantom showed that the activity concentration (AC) values were closest to the true values at low ratios of TBR ( |
| Databáze: | OpenAIRE |
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