Suppression of DRR1 results in the accumulation of insoluble ubiquitinated proteins, which impairs drought stress tolerance
| Autor: | Tae Rin Oh, Woo Taek Kim, Jong Hum Kim, Na Hyun Cho, Seong Gwan Yu |
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| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
0301 basic medicine Drought stress Ubiquitin-Protein Ligases Defence mechanisms Arabidopsis Plant Science Endoplasmic Reticulum 01 natural sciences Biochemistry General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound Ubiquitin Stress Physiological Abscisic acid chemistry.chemical_classification DNA ligase biology Arabidopsis Proteins fungi food and beverages biology.organism_classification Adaptation Physiological Ubiquitinated Proteins Cell biology Droughts 030104 developmental biology Proteotoxicity chemistry Solubility Germination biology.protein 010606 plant biology & botany |
| Zdroj: | Journal of integrative plant biologyREFERENCES. 63(3) |
| ISSN: | 1744-7909 |
| Popis: | Drought stress has detrimental effects on plants. Although the abscisic acid (ABA)-mediated drought response is well established, defensive mechanisms to cope with dehydration-induced proteotoxicity have been rarely studied. DRR1 was identified as an Arabidopsis drought-induced gene encoding an ER-localized RING-type E3 Ub ligase. Suppression of DRR1 markedly reduced tolerance to drought and proteotoxic stress without altering ABA-mediated germination and stomatal movement. Proteotoxicity- and dehydration-induced insoluble ubiquitinated protein accumulation was more obvious in DRR1 loss-of-function plants than in wild-type plants. These results suggest that DRR1 is involved in an ABA-independent drought stress response possibly through the mitigation of dehydration-induced proteotoxic stress. |
| Databáze: | OpenAIRE |
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