A National Survey of Practice Patterns for Accepting Living Kidney Donors With Prior COVID-19
| Autor: | Muhammad S. Yaqub, Tim E. Taber, William C. Goggins, Nicolas Barros, Muhammad A. Mujtaba, Asif Sharfuddin, Areeba Jawed, Vineeta Kumar, Muhammad Y. Jan, Dennis P. Mishler, Oluwafisayo Adebiyi, Alejandro Diez, Melissa Anderson, Jonathan A. Fridell, Krista L. Lentine |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) Practice patterns business.industry pandemic Critical question 030232 urology & nephrology COVID-19 kidney transplantation Perioperative 030204 cardiovascular system & hematology medicine.disease Transplantation 03 medical and health sciences Organ procurement recovered living kidney donors 0302 clinical medicine Nephrology Clinical Research Donation Emergency medicine Medicine business Kidney transplantation living kidney donation |
| Zdroj: | Kidney International Reports |
| ISSN: | 2468-0249 |
| Popis: | Introduction A critical question facing transplant programs is whether, when, and how to safely accept living kidney donors (LKDs) who have recovered from COVID-19 infection. The purpose of the study is to understand current practices related to accepting these LKDs. Methods We surveyed US transplant programs from 3 September through 3 November 2020. Center level and participant level responses were analyzed. Results A total of 174 respondents from 115 unique centers responded, representing 59% of US LKD programs and 72.4% of 2019 and 72.5% of 2020 LKD volume1 (Organ Procurement and Transplantation Network-OPTN 2021). In all, 48.6% of responding centers had received inquiries from such LKDs, whereas 44.3% were currently evaluating. A total of 98 donors were in the evaluation phase, whereas 27.8% centers had approved 42 such donors to proceed with donation. A total of 50.8% of participants preferred to wait >3 months, and 91% would wait at least 1 month from onset of infection to LD surgery. The most common reason to exclude LDs was evidence of COVID-19−related AKI (59.8%) even if resolved, followed by COVID-19−related pneumonia (28.7%) and hospitalization (21.3%). The most common concern in accepting such donors was kidney health postdonation (59.2%), followed by risk of transmission to the recipient (55.7%), donor perioperative pulmonary risk (41.4%), and donor pulmonary risk in the future (29.9%). Conclusion Practice patterns for acceptance of COVID-19−recovered LKDs showed considerable variability. Ongoing research and consensus building are needed to guide optimal practices to ensure safety of accepting such donors. Long-term close follow-up of such donors is warranted. Graphical abstract |
| Databáze: | OpenAIRE |
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